PumpProtect®
PumpProtect®
PumpProtect® – An advanced hypothermic perfusion solution optimized for liver and kidney machine perfusion, featuring balanced electrolytes, physiological pH, and low toxicity for enhanced organ preservation and viability.
PumpProtect® is a sterile, non-toxic, and non-pyrogenic perfusion solution designed for machine perfusion of liver and kidney. It supports in-vitro flushing and continuous preservation with physiological pH (~7.4), potassium (25 mmol/L), sodium (100 mmol/L), and osmolality (~300 mOsm/kg) for optimal organ viability and improved transplant success rates.
- Optimized for machine perfusion
- Potassium 25 mmol/L and Sodium 100 mmol/L
- Osmolality ~300 mOsm/kg
- Physiological pH (~7.4)
- Non-pyrogenic
- Sterile and non-toxic
- Clear to slightly yellow
- Suitable for temporary continuous perfusion
PlegiStore® Composition
| Component | Amount | Concentration |
|---|---|---|
| Calcium Chloride (Dihydrate) | 0.068 g | 0.5 mmol/L |
| HEPES (free acid) | 2.38 g | 10 mmol/L |
| Potassium Phosphate (Monobasic) | 3.4 g | 25 mmol/L |
| Mannitol (USP) | 5.4 g | 30 mmol/L |
| Glucose (Anhydrous), beta D (+) | 1.80 g | 10 mmol/L |
| Sodium Gluconate | 17.45 g | 80 mmol/L |
| Magnesium Gluconate (Anhydrous) | 1.13 g | 5 mmol/L |
| Ribose, D (–) | 0.75 g | 5 mmol/L |
| Pentafraction (HES) | 50.0 g | 50 g/L |
| Glutathione (Reduced form) | 0.92 g | 3 mmol/L |
| Adenine (Free base) | 0.68 g | 5 mmol/L |
| Sodium Hydroxide | qs | pH: 7.4 (adjusted) |
| Water for Injection | qs | 1000 mL |
Storage Conditions
| Parameter | Details |
|---|---|
| Shelf Life | 18 Months |
| Storage Temperature | 2°C to 25°C |
| Special Instructions | Do not freeze |
- FAQs
FAQs Made Simple Here
PumpProtect® is designed for machine perfusion preservation of explanted liver and kidney, supporting flushing and continuous hypothermic perfusion to maintain organ viability before transplantation.
It maintains physiological pH, electrolyte balance, and osmolality, reducing ischemic damage and enhancing cell protection during in-vitro perfusion with pumping devices.
Yes, PumpProtect® is sterile, non-toxic, and non-pyrogenic, ensuring it is safe for use in contact with delicate organ tissues during perfusion.
PumpProtect® is optimized specifically for liver and kidney preservation in machine perfusion systems.
Store PumpProtect® at recommended temperatures between 2°C and 25°C, avoiding freezing to maintain solution stability and efficacy.
Yes, PumpProtect® can be used in research involving organ preservation and transplantation models to evaluate machine perfusion techniques and improve clinical outcomes.
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