Plegistore (HTK Solution)

Plegistore (HTK Solution)

Plegistore (HTK Solution) – Advanced hypothermic perfusion solution. Designed for optimal intracellular-like preservation and safe storage of implanted organs.
Plegistore (HTK Solution) perfusion solution is a sterile, clear to slightly yellow, non-pyrogenic, and non-toxic fluid formulated specifically for the hypothermic flushing and in vitro preservation of implanted organs. With an approximate osmolality of 310 mOsm/kg, it helps maintain cellular integrity. The solution’s pH ranges from 7.02 to 7.20 at room temperature and adjusts to 7.40–7.45 when cooled to 4°C, optimizing organ preservation conditions.

Plegistore (HTK Solution) Composition

CompositionAmountConcentration (mmol/L)
Sodium chloride0.8766 g   15.0 mmol/L
Potassium chloride0.6710 g9.0 mmol/L
Magnesium chloride · 6H₂O0.8132 g4.0 mmol/L
Histidine hydrochloride · H₂O3.7733 g18.0 mmol/L
Histidine27.9289 g180.0 mmol/L
Tryptophan0.4085 g2.0 mmol/L
Mannitol5.4651 g30.0 mmol/L
Calcium chloride · 2H₂O0.0022 g0.015 mmol/L
(Unspecified)0.1842 g1.0 mmol/L
Potassium hydroxide 2Nq.s. to pH adjustment
Water for injectionq.s.1.000 mL

Storage Conditions

Storage ConditionsDetails
Shelf Life12 Months
Temperature2°C to 15°C, Do not Freeze

FAQs Made Simple Here

Plegistore (HTK Solution) is specifically designed for hypothermic flushing and in vitro storage of implanted organs, helping maintain their viability and function during preservation before transplantation.

Yes, Plegistore (HTK Solution) is sterile, non-toxic, and non-pyrogenic, ensuring it does not cause contamination or toxicity, making it safe for preserving delicate implanted organs.

The solution maintains a stable pH between 7.02 and 7.20 at room temperature, which shifts slightly to 7.40–7.45 at 4°C, supporting optimal biochemical balance for preservation.

Plegistore (HTK Solution) has an approximate osmolality of 310 mOsm/kg, which closely mimics physiological conditions, preventing cell swelling or shrinkage during organ preservation.

Yes, it is suitable for hypothermic flushing and storage of various implanted organs, supporting extended preservation across different organ transplant procedures.

Plegistore (HTK Solution) offers advanced intracellular-like preservation, optimal pH and osmolality balance, and sterile, non-toxic formulation, making it a reliable choice for organ storage.

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